Chloroquine pregnancy class

2020-01-29 13:39 Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance Stephen A Ward, Esperanca J P Sevene, Ian M Hastings, Franois Nosten, Rose McGready We review the reproductive toxicology of the main antimalarial drug classes in use studies in which chloroquine has been used in pregnancy,

Appropriate studies performed to date have not demonstrated pediatricspecific problems that would limit the usefulness of chloroquine to prevent and treat malaria in children. However, children are more sensitive to the effects of this medicine than adults. chloroquine pregnancy class

Hydroxychloroquine may benefit pregnancies by reducing active disease of lupus. Hydroxychloroquine may also reduce the chance for a baby to be born with a specific heart conduction problem, called congenital heart block. More studies are needed to understand if hydroxychloroquine helps prevent pregnancy complications.

Hydroxychloroquine Pregnancy Warnings. Use of chloroquine and other 4aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. There are no controlled data in human pregnancy. AU TGA pregnancy category D: Drugs which have caused, chloroquine pregnancy class

Usage in PregnancyUsage of this drug during pregnancy should be avoided except in the suppression or treatment of malaria when in the judgment of the physician the benefit outweighs the possible hazard. Plaquenil and Pregnancy Category C. However, most sources consider it to be a pregnancy Category C medication. In animal studies, it was shown that Plaquenil crosses the placenta and accumulates in the eyes of the fetus and remains there for several months. This raises serious concerns, since Plaquenil is known to cause permanent eye damage. How can the answer be improved? chloroquine pregnancy class NSAIDs and aspirin. After 30 weeks of gestation, NSAIDs and highdose aspirin may increase the risk of a type of fetal heart problem and highdose aspirin may increase the risk for fetal bleeding or bruising. Therefore, in the later stages of pregnancy these drugs become pregnancy category C drugs.

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